New courses added for Fall 2006! : 604b, 606b, 701b
Cell Biology 502 a/b • Molecules to Systems
This full-year course is designed to provide medical students with a current and comprehensive review of
biologic structure and function at the cellular, tissue, and organ system levels. Areas covered include
replication and transcription of the genome; regulation of the cell cycle and mitosis; protein biosynthesis
and membrane targeting; cell motility and the cytoskeleton; signal transduction; nerve and muscle function;
and endocrine and reproductive cell biology. Clinical correlation sessions, which illustrate the
contributions of cell biology to specific medical problems, are interspersed in the lecture schedule.
Histophysiology laboratories provide practical experience with the light microscope for exploring cell
and tissue structure. Note: This course is offered only to MD/PhD Students. J. Jamieson, T. Lentz, F. Gorelick, and staff.
Cell Biology 503 • Histology Laboratory
A laboratory in microscopic anatomy to be taken in conjunction with CBIO 502. Note: This course is offered only to Ph.D. students. T. Lentz and staff.
Cell Biology 601 • Molecular and Cellular Basis of Human Disease
Given in parallel to 502. The course comprises an exploration of primary literature and critical assessment
of the data that form a basis for understanding human disease. A series of human genetic diseases, whose
mechanisms have been identified as a result of sequencing of the human genome, are explored. Students are
required to search out supportive data, discuss it with the session leader, and present it to the group. Note: This course is offered only to full time students at Yale. F. Gorelick and staff.
Cell Biology 602a • Molecular Cell Biology
A comprehensive introduction to the molecular and mechanistic aspects of cell biology
for graduate students in all programs. Emphasizes fundamental issues of cellular organization, regulation,
biogenesis, and function at the molecular level. Also MB&B 602a, MCDB 602a. S. Wolin, T. Pollard, G. Warren,
M. Mooseker.
Cell Biology 603a • Seminar in Molecular Cell Biology
A graduate level seminar course in modern cell biology. The class is
devoted to the reading and critical evaluation of classical and current papers. The topics are coordinated
with the CBIO 602a lecture schedule. Thus, concurrent or previous enrollment in CBIO 602a is required. Also
MCDB 603a. S. Wolin, T. Pollard, G. Warren, M. Mooseker.
Cell Biology 604b • Systems Cell Biology
Introduction to the organization and function of cells within complex multicellular systems as encountered in the human body. Covers major tissues and organs as well as the cardiovascular, immune and nervous systems, with special emphasis on the molecular and cellular bases of developmental processes and human diseases. Lectures supplemented by electronic-based tutorials on the histology of tissues and organs. C. Hashimoto and faculty.
Cell Biology 606b • Advanced Seminar Course
This seminar course, which meets once a week, covers several topics suggested by the second-year cell biology students. It should serve to introduce students to areas they might not have considered in prior courses. Each topic is spread over 3–4 sessions, starting with an introductory overview and followed by a detailed analysis of key papers. S. Ferro-Novick, P. Novick
Cell Biology 701b • Illuminating Cellular Function
Introduction to the principles and practical methods of live cell imaging. Covers principles of contrast generation (including genetically encoded probes and physiological indicators), image formation, image detection, and image analysis. Includes hands-on demonstrations of state-of-the-art instrumentation, such as video-rate confocal and multi-photon microscopes. G. Miesenböck, D. Toomre, and faculty.
Cell Biology 900a and 901b • First Year Introduction to Research
Lab rotations, Grant Writing and Ethics for Molecular Cell Biology, Genetics and Development Track students.
Also GENE 900a and 901b, MCDB 900a and 901b. C. Hashimoto, F. Slack, M. Stern, and faculty.
